4-Methylbenzylidene camphor

产品说明书

Print
Chemical Structure| 36861-47-9 同义名 : 3-(4-甲基苯亚甲基)樟脑 ;4-MBC; Enzacamene; Uvinul MBC 95; Parsol 500; Neo Heliopan MBC; Eusolex 6300
CAS号 : 36861-47-9
货号 : A106890
分子式 : C18H22O
纯度 : 98%
分子量 : 254.37
MDL号 : MFCD00209662
存储条件:

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(412.78 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

生物活性
描述 4-Methylbenzylidene camphor (4-MBC), functioning as an endocrine disruptor, mimics estrogen and impacts human trophoblast cells by reducing their proliferation and triggering apoptosis. It activates the PI3K/AKT and ERK1/2 signaling pathways and increases the production of intracellular reactive oxygen species (ROS). As a UV filter, 4-MBC could interfere with normal placental development in early pregnancy[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.93mL

0.79mL

0.39mL

19.66mL

3.93mL

1.97mL

39.31mL

7.86mL

3.93mL

参考文献

[1]Changwon Yang, et al. 4-Methylbenzylidene-camphor inhibits proliferation and induces reactive oxygen species-mediated apoptosis of human trophoblast cells. Reprod Toxicol. 2019 Mar:84:49-58.

[2]Margret Schlumpf, et al. Developmental toxicity of UV filters and environmental exposure: a review. Int J Androl. 2008 Apr;31(2):144-51.