Loganin

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Chemical Structure| 18524-94-2 同义名 : Loganoside; NSC 606403; 7-hydroxy-6-desoxy Verbenalin
CAS号 : 18524-94-2
货号 : A106244
分子式 : C17H26O10
纯度 : 99%+
分子量 : 390.38
MDL号 : MFCD00075645
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(128.08 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
靶点

  • AChE

    AChE, IC50:3.95 μM
描述 Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.56mL

0.51mL

0.26mL

12.81mL

2.56mL

1.28mL

25.62mL

5.12mL

2.56mL
参考文献

[1]Yao L, Peng SX, et al. Unexpected Neuroprotective Effects of Loganin on 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurotoxicity and Cell Death in Zebrafish. J Cell Biochem. 2017 Mar;118(3):615-628.

[2]Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50.