6-Gingerol
产品说明书
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同义名 : | 6-姜辣素 ;(S)-(+)-[6]Gingerol; [6]-Gingerol |
| CAS号 : | 23513-14-6 | |
| 货号 : | A103354 | |
| 分子式 : | C17H26O4 | |
| 纯度 : | 99%+ | |
| 分子量 : | 294.39 | |
| MDL号 : | MFCD00210507 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(169.85 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | 6-Gingerol, a pungent oil of fresh ginger, reduces biofilm formation and virulence by antagonistically binding to P. aeruginosa QS receptors. The height of the biofilm formed with 10 μM and 0 μM 6-gingerol was ~12 and ~25 μm, respectively. The growth of Pseudomonas aeruginosa was slightly inhibited by 0.1-100 μ m 6-gingerol[3]. Moreover,6-gingerol exhibited protective effects on apoptosis induced by Aβ1–42 in cultured PC12 cells by reducing oxidative stress and inflammatory responses, suppressing the activation of GSK-3β and enhancing the activation of Akt[4]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT03268655 | Colorectal Adenoma | Not Applicable | Not yet recruiting | February 2020 | United States, Minnesota ... 展开 >> Epidemiology Clinical Research Center Minneapolis, Minnesota, United States, 55415 收起 << |
| NCT03089593 | Healthy Volunteers | Not Applicable | Completed | - | Brazil ... 展开 >> Hospital das Clínicas Belo Horizonte, Minas Gerais, Brazil, 30130-100 收起 << |
| NCT03028454 | Muscle Soreness | Not Applicable | Completed | - | United States, Virginia ... 展开 >> Human Performance Laboratory Norfolk, Virginia, United States, 23529 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.40mL 0.68mL 0.34mL |
16.98mL 3.40mL 1.70mL |
33.97mL 6.79mL 3.40mL |
| 参考文献 |
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