C-178
产品说明书
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同义名 : | STING inhibitor C-178 |
| CAS号 : | 329198-87-0 | |
| 货号 : | A991151 | |
| 分子式 : | C17H10N2O5 | |
| 纯度 : | 99%+ | |
| 分子量 : | 322.27 | |
| MDL号 : | MFCD01146392 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 40 mg/mL(124.12 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | C-178 functions as a powerful and specific covalent inhibitor targeting STING. It forms a bond with Cys91, effectively dampening STING reactions triggered by various authentic activators in mice but not in humans [1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.10mL 0.62mL 0.31mL |
15.51mL 3.10mL 1.55mL |
31.03mL 6.21mL 3.10mL |
| 参考文献 |
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