Irisflorentin

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Chemical Structure| 41743-73-1 同义名 : -
CAS号 : 41743-73-1
货号 : A957674
分子式 : C20H18O8
纯度 : 99%
分子量 : 386.35
MDL号 : MFCD02183467
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(129.42 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Irisflorentin, a natural product isolated and purified from the rhizomes of Belamcanda chinensis (L.) DC., has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.59mL

0.52mL

0.26mL

12.94mL

2.59mL

1.29mL

25.88mL

5.18mL

2.59mL
参考文献

[1]Chen YM, Liu SP, et al. Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson's disease therapy.Biomedicine (Taipei). 2015;5(1):4.

[2]Fu RH, Tsai CW, et al. Irisflorentin modifies properties of mouse bone marrow-derived dendritic cells and reduces the allergic contact hypersensitivity responses. Cell Transplant. 2015;24(3):573-88.