Talaporfin sodium

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Chemical Structure| 220201-34-3 同义名 : ME2906; Mono-L-aspartyl chlorin e6; Taporfin; Talaporfin (sodium salt); NPe6
CAS号 : 220201-34-3
货号 : A949327
分子式 : C38H37N5Na4O9
纯度 : 98+%
分子量 : 799.69
MDL号 : N/A
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 2 mg/mL(2.5 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 25 mg/mL(31.26 mM)，配合低频超声助溶
生物活性
描述 Talaporfin is a photosensitizer used in photodynamic therapy (PDT).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.25mL

0.25mL

0.13mL

6.25mL

1.25mL

0.63mL

12.50mL

2.50mL

1.25mL
参考文献

[1]Ikeda H, Ohba S, et al. The effect of photodynamic therapy with talaporfin sodium, a second-generation photosensitizer, on oral squamous cell carcinoma: A series of eight cases. Photodiagnosis Photodyn Ther. 2017 Nov 30. pii: S1572-1000(17)30448-9.

[2]Doi M, Ogawa E, et al. Effect of a photosensitization reaction performed during the first 3 min after exposure of rat myocardial cells to talaporfin sodium in vitro. Lasers Med Sci. 2017 Nov;32(8):1873-1878.