Galidesivir

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Chemical Structure| 249503-25-1 同义名 : BCX4430; Immucillin-A
CAS号 : 249503-25-1
货号 : A918957
分子式 : C11H15N5O3
纯度 : 99%
分子量 : 265.27
MDL号 : MFCD28385877
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 100 mg/mL(376.98 mM)，配合低频超声助溶
生物活性
描述 BCX 4430 free base is a viral RNA-dependent RNA polymerase (RdRp) inhibitor and demonstrates broad-spectrum activity in multiple viruses and a favorable preliminary preclinical safety profile.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.77mL

0.75mL

0.38mL

18.85mL

3.77mL

1.88mL

37.70mL

7.54mL

3.77mL
参考文献

[1]Smee DF, Hurst BL, et al. Evaluation of cell viability dyes in antiviral assays with RNA viruses that exhibit different cytopathogenic properties. J Virol Methods. 2017 Aug;246:51-57.