Tiliroside

产品说明书

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Chemical Structure| 20316-62-5 同义名 : 银椴甙;椴树苷;银锻苷 ;Kaempferol 3-O-β-D-Glucopyranoside-6-p-coumaril ester; Kaempferol 3-O-β-D-(6''-E-p-coumaroyl)-glucopyranoside
CAS号 : 20316-62-5
货号 : A913539
分子式 : C30H26O13
纯度 : 99%+
分子量 : 594.52
MDL号 : MFCD00017454
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(420.51 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Tiliroside, a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb. with anticarcinogenic, hepatoprotective, antioxidant and anti-inflammatory activities, can enhance fatty acid oxidation via the enhancement adiponectin signaling associated with the activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.68mL

0.34mL

0.17mL

8.41mL

1.68mL

0.84mL

16.82mL

3.36mL

1.68mL
参考文献

[1]Velagapudi R, Aderogba M, Olajide OA. Tiliroside, a dietary glycosidic flavonoid, inhibits TRAF-6/NF-κB/p38-mediated neuroinflammation in activated BV2 microglia. Biochim Biophys Acta. 2014 Dec;1840(12):3311-9.

[2]Goto T, Teraminami A, et al. Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice. J Nutr Biochem. 2012 Jul;23(7):768-76.