L-O-Phosphoserine

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Chemical Structure| 407-41-0 同义名 : 磷酸化丝氨酸 ;O-Phospho-L-serine; L-Serine O-phosphate; Phosphoserine; Plasmenylserine; Dexfosfoserine; L-SOP
CAS号 : 407-41-0
货号 : A904542
分子式 : C3H8NO6P
纯度 : 95%
分子量 : 185.07
MDL号 : MFCD00065935
存储条件:

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 O-Phospho-L-serine serves as the direct forerunner of L-serine in the pathway of serine synthesis and functions as an activator for the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8). Additionally, it acts as a mild inhibitor for mGluR1 and a strong inhibitor for mGluR2[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.40mL

1.08mL

0.54mL

27.02mL

5.40mL

2.70mL

54.03mL

10.81mL

5.40mL

参考文献

[1]Kang HJ, et al. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30;290(5):2870-8.

[2]Kang HJ, et al. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24;289(43):29961-74.

[3]Zhiqing Yuan, et al. 9-cis-retinoic Acid Elevates MRP3 Expression by Inhibiting Sumoylation of RXRα to Alleviate Cholestatic Liver Injury. Biochem Biophys Res Commun. 2018 Sep 3;503(1):188-194.