生物活性 | |||
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描述 | Octadecanal is a long-chain aldehyde and the principal free fatty aldehydes present[1]. Intact SLS (Sjögren-Larsson syndrome) fibroblasts oxidized octadecanol to fatty acid at less than 10% of the normal rate, but oxidized free octadecanal normally, suggesting that the FALDH (fatty aldehyde dehydrogenase) affected in SLS is chiefly involved in the oxidation of fatty alcohol to fatty acid[2]. With octadecanal, a burst phase of product formation, k(prod) = 3.4 ± 0.5 min(-1), is observed, indicating that chemistry is not rate-determining under the conditions of the assay[3]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.72mL 0.74mL 0.37mL |
18.62mL 3.72mL 1.86mL |
37.25mL 7.45mL 3.72mL |
参考文献 |
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