Leonurine HCl

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Chemical Structure| 24735-18-0 同义名 : SCM-198 hydrochloride; SCM-198 HCl
CAS号 : 24735-18-0
货号 : A852193
分子式 : C14H22ClN3O5
纯度 : 99%
分子量 : 347.79
MDL号 : MFCD09953249
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 30 mg/mL(86.26 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 5 mg/mL(14.38 mM)，配合低频超声助溶
生物活性
描述 Leonurine hydrochloride is a major alkaloid compound extracted fromLeonurus japonicasHoutt.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.88mL

0.58mL

0.29mL

14.38mL

2.88mL

1.44mL

28.75mL

5.75mL

2.88mL
参考文献

[1]Mao F, Zhang L, et al. Leonurine hydrochloride induces apoptosis of H292 lung cancer cell by a mitochondria-dependent pathway. Pharm Biol. 2015;53(11):1684-90.

[2]Yuan FL, Xu RS, et al. Leonurine hydrochloride inhibits osteoclastogenesis and prevents osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways. Bone. 2015 Jun;75:128-37.