2-TEDC

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Chemical Structure| 132465-10-2 同义名 : -
CAS号 : 132465-10-2
货号 : A834096
分子式 : C16H13NO4S
纯度 : 99%
分子量 : 315.34
MDL号 : MFCD00894731
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(332.97 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 2-TEDC is recognized as a strong inhibitor of the enzymes 5-, 12-, and 15-lipoxygenase, exhibiting IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively. It is applicable in the study of atherosclerosis[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.17mL

0.63mL

0.32mL

15.86mL

3.17mL

1.59mL

31.71mL

6.34mL

3.17mL
参考文献

[1]H Cho, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991 Apr;34(4):1503-5.