Metiamide

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Chemical Structure| 34839-70-8 同义名 : SK&F 92058
CAS号 : 34839-70-8
货号 : A834014
分子式 : C9H16N4S2
纯度 : 98%+
分子量 : 244.38
MDL号 : MFCD00867517
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 2 mg/mL(8.18 mM),配合低频超声,并水浴加热至45℃助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

H2O: 1.5 mg/mL(6.14 mM),配合低频超声,并水浴加热至45℃助溶

动物实验配方:
生物活性
描述 JC-1 (CBIC2) serves as an ideal fluorescent probe for detecting mitochondrial membrane potential, accumulating in mitochondria in a potential-dependent manner. It can be used to assess the membrane potential of cells, tissues, or purified mitochondria. In healthy mitochondria, JC-1 aggregates in the mitochondrial matrix, forming a polymer that emits strong red fluorescence; when mitochondrial membrane potential decreases, JC-1 cannot aggregate, producing green fluorescence instead[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.09mL

0.82mL

0.41mL

20.46mL

4.09mL

2.05mL

40.92mL

8.18mL

4.09mL

参考文献

[1]Alexandra Kikonyogo ,Regina Pietruszko, Cimetidine and Other H2-Receptor Antagonists as Inhibitors of Human E3 Aldehyde Dehydrogenase. Molecular Pharmacology 1997; 52: 2267-271.