Damascenone

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Chemical Structure| 23696-85-7 同义名 : 大马烯酮 ;(E/Z)-Damascenone
CAS号 : 23696-85-7
货号 : A831014
分子式 : C13H18O
纯度 : 97%
分子量 : 190.28
MDL号 : MFCD00101024
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(551.81 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Damascenone is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes[1]. A detailed investigation into the effect of SO2 demonstrated that loss of damascenone in model wine was directly related to the concentration of added SO2 but was essentially unaffected by small changes in pH[2]. The effect of β-damascenone on Pinot noir aroma was less clear, as perception seems to be heavily influenced by wine matrix composition[3]. In hydroalcoholic solution, beta-damascenone (Damascenone) enhanced fruity notes of ethyl cinnamate and caproate and masked the herbaceous aroma of IBMP[4]. UVR-induced sunburn was prevented by a single oral β-damascenone dose as low as 20 μL (0.95 mg/g body weight)[5].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.26mL

1.05mL

0.53mL

26.28mL

5.26mL

2.63mL

52.55mL

10.51mL

5.26mL
参考文献

[1]Sefton MA, Skouroumounis GK, Elsey GM, Taylor DK. Occurrence, sensory impact, formation, and fate of damascenone in grapes, wines, and other foods and beverages. J Agric Food Chem. 2011 Sep 28;59(18):9717-46

[2]Daniel MA, Elsey GM, Capone DL, Perkins MV, Sefton MA. Fate of damascenone in wine: the role of SO2. J Agric Food Chem. 2004 Dec 29;52(26):8127-31

[3]Tomasino E, Bolman S. The Potential Effect of β-Ionone and β-Damascenone on Sensory Perception of Pinot Noir Wine Aroma. Molecules. 2021 Feb 27;26(5):1288

[4]Pineau B, Barbe JC, Van Leeuwen C, Dubourdieu D. Which impact for beta-damascenone on red wines aroma? J Agric Food Chem. 2007 May 16;55(10):4103-8

[5]Uddin AN, Labuda I, Burns FJ. A novel mechanism of filaggrin induction and sunburn prevention by β-damascenone in Skh-1 mice. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):335-41