MK-1064
产品说明书
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同义名 : | - |
| CAS号 : | 1207253-08-4 | |
| 货号 : | A827816 | |
| 分子式 : | C24H20ClN5O3 | |
| 纯度 : | 97% | |
| 分子量 : | 461.9 | |
| MDL号 : | MFCD28502027 | |
| 存储条件： |
Pure form Inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 50 mg/mL(108.25 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | MK-1064 serves as a specific, orally effective OX2R antagonist, with a Ki of 0.5 nM and an IC50 of 18 nM, and is observed to facilitate sleep in live models, suggesting its potential for insomnia research[1].[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.16mL 0.43mL 0.22mL |
10.82mL 2.16mL 1.08mL |
21.65mL 4.33mL 2.16mL |
| 参考文献 |
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