ACY-957
产品说明书
 |
同义名 : | HDAC Inhibitor C001 |
| CAS号 : | 1609389-52-7 | |
| 货号 : | A792202 | |
| 分子式 : | C24H23N5OS | |
| 纯度 : | 98% | |
| 分子量 : | 429.54 | |
| MDL号 : | MFCD30342405 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 85 mg/mL(197.89 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | HDAC inhibitor C001 is an inhibitor of HDACs with IC50 of 4 nM (HDAC1), 15 nM (HDAC2), 114 nM (HDAC3), and can increase Gata2 expression, which may be useful in treatment of Gata2-deficiency-associated diseases, including leukemia and other blood cell disorders. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.33mL 0.47mL 0.23mL |
11.64mL 2.33mL 1.16mL |
23.28mL 4.66mL 2.33mL |
| 参考文献 |
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