4-(Trifluoromethyl)umbelliferone

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Chemical Structure| 575-03-1 同义名 : -
CAS号 : 575-03-1
货号 : A773520
分子式 : C10H5F3O3
纯度 : 98%
分子量 : 230.14
MDL号 : MFCD00037578
存储条件:

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(456.24 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

生物活性
描述 4-(Trifluoromethyl)umbelliferone serves as a fluorescent probe substrate specifically for rat hepatic cytochrome P450 enzymes[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.35mL

0.87mL

0.43mL

21.73mL

4.35mL

2.17mL

43.45mL

8.69mL

4.35mL

参考文献

[1]Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78.