Fluvoxamine

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Chemical Structure| 54739-18-3 同义名 : DU-23000
CAS号 : 54739-18-3
货号 : A745373
分子式 : C15H21F3N2O2
纯度 : 99%
分子量 : 318.33
MDL号 : MFCD00865345
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 155 mg/mL(486.91 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00716820 - Completed - -
NCT00716820 - Completed - -
NCT00716625 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.14mL

0.63mL

0.31mL

15.71mL

3.14mL

1.57mL

31.41mL

6.28mL

3.14mL
参考文献

[1]Ginsburg BC, Pinkston JW, et al. The potency of fluvoxamine to reduce ethanol self-administration decreases with concurrent availability of food. Behav Pharmacol. 2012 Apr;23(2):134-42.

[2]Escalona R, Canive JM, et al. Fluvoxamine treatment in veterans with combat-related post-traumatic stress disorder. Depress Anxiety. 2002;15(1):29-33.