Bilobetin

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Chemical Structure| 521-32-4 同义名 : 白果双黄酮
CAS号 : 521-32-4
货号 : A744388
分子式 : C31H20O10
纯度 : 98+%
分子量 : 552.48
MDL号 : MFCD00597036
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 250 mg/mL(452.5 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Bilobetin, a natural product isolated and purified from the leaves of Ginkgo biloba L., whose treatment ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats by stimulating PPARα-mediated lipid catabolism.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.81mL

0.36mL

0.18mL

9.05mL

1.81mL

0.91mL

18.10mL

3.62mL

1.81mL
参考文献

[1]Kou XH, Zhu MF, et al. Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. Br J Pharmacol. 2012 Apr;165(8):2692-706.

[2]Briancon-Scheid F, Lobstein-Guth A, Anton R. HPLC Separation and Quantitative Determination of Biflavones in Leaves from Ginkgo biloba. Planta Med. 1983 Dec;49(12):204-7.