Azido-PEG4-Boc

产品说明书

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Chemical Structure| 581066-04-8 同义名 : -
CAS号 : 581066-04-8
货号 : A742879
分子式 : C15H29N3O6
纯度 : 95%
分子量 : 347.41
MDL号 : MFCD18916988
存储条件:

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Azido-PEG4-Boc serves as a PEG-based PROTAC linker for PROTAC synthesis[1]. Azido-PEG4-Boc serves as a click chemistry reagent, housing an Azide moiety capable of engaging in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-functionalized molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules carrying DBCO or BCN groups.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.88mL

0.58mL

0.29mL

14.39mL

2.88mL

1.44mL

28.78mL

5.76mL

2.88mL

参考文献

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562