Calcifediol-d6

产品说明书

Print
Chemical Structure| 78782-98-6 同义名 : 25-hydroxy Vitamin D3-d6
CAS号 : 78782-98-6
货号 : A724658
分子式 : C27H44O2
纯度 : 98% +98%atom%D
分子量 : 406.67
MDL号 : MFCD15071183
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(258.19 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Calcifediol-d6 is the deuterium-labeled version of Calcifediol. Calcifediol, a principal circulating metabolite of vitamin D3, acts as a potent inhibitor of the Vitamin D Receptor (VDR)[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.46mL

0.49mL

0.25mL

12.29mL

2.46mL

1.23mL

24.59mL

4.92mL

2.46mL
参考文献

[1]Trifu V, et al. Cortexolone 17伪-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0路05% cream. Br J Dermatol. 2011 Jul;165(1):177-83.

[2]Trifu V, et al. Cortexolone 17α-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0•05% cream. Br J Dermatol. 2011 Jul;165(1):177-83.