Asiatic acid
产品说明书
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同义名 : | Dammarolic Acid; Asiantic acid; NSC 166063 |
| CAS号 : | 464-92-6 | |
| 货号 : | A719831 | |
| 分子式 : | C30H48O5 | |
| 纯度 : | 98+% | |
| 分子量 : | 488.7 | |
| MDL号 : | MFCD00238541 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 250 mg/mL(511.56 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Asiatic acid, a pentacyclic triterpene from Centella asiatica, exhibits anticancer activities, induces apoptosis in melanoma cells, and provides barrier protective effects in human aortic endothelial cells (HAEC). It also demonstrates anti-inflammatory properties by inhibiting TNF-α-induced endothelial barrier dysfunction and the NLRP3 inflammasome activation along with the NF-κB pathway. These actions result in significant inflammation reduction in rats and offer neuroprotection in rat spinal cord injury models[1][2][3][4][5]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.05mL 0.41mL 0.20mL |
10.23mL 2.05mL 1.02mL |
20.46mL 4.09mL 2.05mL |
| 参考文献 |
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