MTX-211
产品说明书
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同义名 : | Mol 211 |
| CAS号 : | 1952236-05-3 | |
| 货号 : | A709001 | |
| 分子式 : | C20H14Cl2FN5O2S | |
| 纯度 : | 98% | |
| 分子量 : | 478.33 | |
| MDL号 : | MFCD31620832 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 12 mg/mL(25.09 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
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| 靶点 |
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| 描述 | MTX-211, also known as Mol 211, is a dual inhibitor of epidermal growth factor receptor and PI3K with an IC50 value of <100 nM. MTX-211 can be used in the study of cancer and other diseases[1].MTX-211 has inhibitory activity against both epidermal growth factor receptor and PI3K alpha with an IC50 value of <100 nM[1]. | ||
| 实验方案 | |||
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| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.45mL 2.09mL 1.05mL |
20.91mL 4.18mL 2.09mL |
| 参考文献 |
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[1]Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2 |