14-Deoxyandrographolide
产品说明书
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同义名 : | 去氧穿心莲内酯 ;14-DAG |
| CAS号 : | 4176-97-0 | |
| 货号 : | A701951 | |
| 分子式 : | C20H30O4 | |
| 纯度 : | 98+% | |
| 分子量 : | 334.45 | |
| MDL号 : | MFCD01861504 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(313.95 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm. f.) Nees with hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, probably providing a promising approach in the prevention of liver diseases during chronic alcoholism, and desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.99mL 0.60mL 0.30mL |
14.95mL 2.99mL 1.49mL |
29.90mL 5.98mL 2.99mL |
| 参考文献 |
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