Trilobatin

产品说明书

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Chemical Structure| 4192-90-9 同义名 : 三叶苷 ;Phloretin-4-O-glucoside; P-Phlorizin; Phloretin-4-O-glucoside, Trilobatin
CAS号 : 4192-90-9
货号 : A671271
分子式 : C21H24O10
纯度 : 99%+
分子量 : 436.41
MDL号 : MFCD21333313
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(240.6 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Trilobatin, a natural product isolated and purified from the herbs of Lithocarpus pachyphyllus with anti-oxidant effect, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway and is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.29mL

0.46mL

0.23mL

11.46mL

2.29mL

1.15mL

22.91mL

4.58mL

2.29mL
参考文献

[1]Fan X, Zhang Y, et al. Trilobatin attenuates the LPS-mediated inflammatory response by suppressing the NF-κB signaling pathway. Food Chem. 2015 Jan 1;166:609-15.

[2]Yang WM, Liu JK, et al. Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. Z Naturforsch C. 2004 Jul-Aug;59(7-8):481-4.