Eugenol
产品说明书
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同义名 : | 4-烯丙基-2-甲氧基苯酚 ;4-Allyl-2-methoxyphenol; 4-Allylguaiacol; NSC 209525; Allylguaiacol; Eugenic acid |
| CAS号 : | 97-53-0 | |
| 货号 : | A671082 | |
| 分子式 : | C10H12O2 | |
| 纯度 : | 98% | |
| 分子量 : | 164.2 | |
| MDL号 : | MFCD00008654 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(639.46 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
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| 动物实验配方： |
| 生物活性 | |||
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| 描述 | Eugenol is a phenolic compound from the class of phenylpropanoids and the main component of clove[3]. Eugenol and its related compounds are effective antioxidants that can prevent free radical-mediated diseases[4]. Eugenol's ability to sequester free radicals in the DPPH assay (IC50 = 11.7 μg/mL), as well as to inhibit reactive oxygen species (ROS) (IC50 = 1.6 μg/mL), H2O2 (IC50 = 22.6 μg/mL and 27.1 μg/mL), and NO (IC50< 50.0 μg/mL)[3].in vitro,the fluorescence of eugenol decreased with the increase of insulin concentration. The values of Ksv and kq were found to be 2.5 × 105 L mol−1 and 2.5 × 1013 L mol−1 s−1 respectively[5]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02346227 | Uterine Cervical Dysplasia ... 展开 >> Papillomavirus Infections 收起 << | Phase 3 | Completed | - | Congo, The Democratic Republic... 展开 >> of the Centre de Santé Lisungi Kinshasa, Mont-Ngafula, Congo, The Democratic Republic of the, Route Kimwenza n°23 收起 << |
| NCT03166748 | Pulpotomy of Immature Lower Fi... 展开 >>rst Molar(Apexegenesis) 收起 << | Not Applicable | Not yet recruiting | August 2018 | - |
| NCT02652403 | Edentulous | Phase 2 | Completed | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
6.09mL 1.22mL 0.61mL |
30.45mL 6.09mL 3.05mL |
60.90mL 12.18mL 6.09mL |
| 参考文献 |
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