D-Galactose

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Chemical Structure| 59-23-4 同义名 : D-(+)-半乳糖 ;D-Galactopyranose; D-(+)-Galactose
CAS号 : 59-23-4
货号 : A665119
分子式 : C6H12O6
纯度 : 95%
分子量 : 180.16
MDL号 : MFCD00151230
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(277.54 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 60 mg/mL(333.04 mM)，配合低频超声，并水浴加热至45℃助溶
生物活性
描述 D-Galactose is a naturally occurring aldohexose and the C-4 epimer of glucose.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.55mL

1.11mL

0.56mL

27.75mL

5.55mL

2.78mL

55.51mL

11.10mL

5.55mL
参考文献

[1]Csiszovszki Z, et al. Structure and function of the D-galactose network in enterobacteria. MBio. 2011 Jun 28;2(4):e00053-11.

[2]Cui X, et al. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidativedamage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res. 2006 Aug 15;84(3):647-54.

[3]Budni J, et al. Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats. Behav Brain Res. 2016 Apr 1;302:35-43.

[4]Haifeng Wei, et al. Behavioural study of the Haifeng Wei, et al. Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav Brain Res. 2005, 157, 22.

[5]Saida Haider, et al. A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process. Life Sci. 2015.

[6]Wenjing Feng, et al. Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. Curr Eye Res. 2021, 46, 6.

[7]Lei Zhong, et al. Characterization of an i.p. D-galactose-induced cataract model in rats. J Pharmacol Toxicol Methods. 2021.

[8]Haider S, Liaquat L, Shahzad S, Sadir S, Madiha S, Batool Z, Tabassum S, Saleem S, Naqvi F, Perveen T. A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process. Life Sci. 2015 Mar 1;124:110-9.

[9]Zhong L, Wang T, Wang T, et al. Characterization of an i.p. D-galactose-induced cataract model in rats. J Pharmacol Toxicol Methods. 2021;107:106891.