1-Hydroxyrutecarpine

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Chemical Structure| 53600-24-1 同义名 : 1-Hydroxyrutaecarpine
CAS号 : 53600-24-1
货号 : A641756
分子式 : C18H13N3O2
纯度 : 98+%
分子量 : 303.31
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 1-Hydroxyrutaecarpine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth., exhibits cytotoxicities (ED50 values < 4 mg/mL) against P-388 or HT-29 cell lines in vitro and antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 mg/mL. 1-Hydroxyrutaecarpine also displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/mL.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.30mL

0.66mL

0.33mL

16.48mL

3.30mL

1.65mL

32.97mL

6.59mL

3.30mL
参考文献

[1]Chen JJ, Fang HY, et al. New indolopyridoquinazoline, benzo[c] phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum. Planta Med. 2005 May;71(5):470-5.

[2]Sheen WS, Tsai IL, et al. Indolopyridoquinazoline alkaloids with antiplatelet aggregation activity from Zanthoxylum integrifoliolum. PlantaMed. 1996 Apr;62(2):175-6.