Leucomethylene blue mesylate
产品说明书
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同义名 : | TRx0237 mesylate; Methylene blue leuco base mesylate; LMTM; Leukomethylthioninium dihydromesylate; Leucomethylene Blue; Hydromethylthionine; TRx0237 (mesylate); Hydromethylthionine mesylate |
| CAS号 : | 1236208-20-0 | |
| 货号 : | A611795 | |
| 分子式 : | C18H27N3O6S3 | |
| 纯度 : | 98% | |
| 分子量 : | 477.62 | |
| MDL号 : | MFCD29764308 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(219.84 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO H2O: 85 mg/mL(177.97 mM)，配合低频超声助溶 |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Leucomethylene blue mesylate, a common reduced form of methylene blue, is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.47mL 2.09mL 1.05mL |
20.94mL 4.19mL 2.09mL |
| 参考文献 |
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