Isocorynoxeine

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Chemical Structure| 51014-29-0 同义名 : 7-Isocorynoxeine
CAS号 : 51014-29-0
货号 : A607889
分子式 : C22H26N2O4
纯度 : 99%+
分子量 : 382.45
MDL号 : MFCD20527292
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 25 mg/mL(65.37 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Isocorynoxeine, a major alkaloid found in Uncaria rhynchophylla, exhibits wide beneficial effects on the cardiovascular and cardiocerebral vascular systems.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.61mL

0.52mL

0.26mL

13.07mL

2.61mL

1.31mL

26.15mL

5.23mL

2.61mL
参考文献

[1]Chen YP, Lu MN, et al. Metabolites of isocorynoxeine in rats after its oral administration. J Asian Nat Prod Res. 2015;17(4):384-90.

[2]Qi W, Chen F, et al. Isolation and identification of twelve metabolites of isocorynoxeine in rat urine and their neuroprotective activities in HT22 cell assay. Planta Med. 2015 Jan;81(1):46-55.