CycLuc1

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Chemical Structure| 1247879-16-8 同义名 : -
CAS号 : 1247879-16-8
货号 : A599955
分子式 : C13H11N3O2S2
纯度 : 98%+
分子量 : 305.38
MDL号 : MFCD28133582
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 85 mg/mL(278.35 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 CycLuc1 is a luciferase substrate that crosses the blood-brain barrier and emits near-infrared (NIR) fluorescence with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.27mL

0.65mL

0.33mL

16.37mL

3.27mL

1.64mL

32.75mL

6.55mL

3.27mL
参考文献

[1]Shiv K, et al. Abstract 4112: Synthetic luciferin, CycLuc1, improves bioluminescence imaging for intracranial glioblastoma xenografts. 10.1158/1538-7445.AM2018-4112

[2]Evans MS, et al. A synthetic luciferin improves bioluminescence imaging in live mice. Nat Methods. 2014 Apr;11(4):393-5. doi: 10.1038/nmeth.2839. Epub 2014 Feb 9. Erratum in: Nat Methods. 2014 Apr;11(4):395.