Guaiol

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Chemical Structure| 489-86-1 同义名 : 愈创醇 ;Champacol; Guaiac alcohol; NSC 19941
CAS号 : 489-86-1
货号 : A581815
分子式 : C15H26O
纯度 : 99%
分子量 : 222.37
MDL号 : MFCD00043336
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 35 mg/mL(157.4 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Guaiol, a natural product isolated and purified from the roots of Ferula ferulaeoides with insecticidal activity, shows significant inhibition of aphids at a concentration of 70 mg/L and good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae of M. separata and adult Musca domestica, with LC50 values of 3.5 microL/L and 16.9 microL/L, respectively.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.50mL

0.90mL

0.45mL

22.49mL

4.50mL

2.25mL

44.97mL

8.99mL

4.50mL
参考文献

[1]Liu T, Wang CJ, et al. Guaiol--a naturally occurring insecticidal sesquiterpene. Nat Prod Commun. 2013 Oct;8(10):1353-4.

[2]Miyazawa M, Sugawara A. Biotransformation of (-)-guaiol by Eurotium rubrum as a biocatalyst. Nat Prod Res. 2006 Jul 10;20(8):731-4.