Vaccarin

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Chemical Structure| 53452-16-7 同义名 : -
CAS号 : 53452-16-7
货号 : A579490
分子式 : C32H38O19
纯度 : 99%+
分子量 : 726.63
MDL号 : MFCD20487836
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(165.15 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Vaccarin, a natural product isolated and purified from the seeds of Vaccaria segetalis, can significantly promote neovascularization by enhancing protein expression of p-Akt , p‑Erk, and CD31, and may be able to selectively protect vascular endothelium from dysfunction induced by H2O2.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.38mL

0.28mL

0.14mL

6.88mL

1.38mL

0.69mL

13.76mL

2.75mL

1.38mL
参考文献

[1]Xie F, Feng L, et al. Vaccarin promotes endothelial cell proliferation in association with neovascularization in vitro and in vivo. Mol Med Rep. 2015 Jul;12(1):1131-6. doi: 10.3892/mmr.2015.3503.

[2]Xie F, Cai W, et al. Vaccarin attenuates the human EA.hy926 endothelial cell oxidative stress injury through inhibition of Notch signaling. Int J Mol Med. 2015 Jan;35(1):135-42.