2-Iodoacetamide

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Chemical Structure| 144-48-9 同义名 : 2-碘乙酰胺 ;Iodoacetamide; IA; IAM
CAS号 : 144-48-9
货号 : A576369
分子式 : C2H4INO
纯度 : 98%
分子量 : 184.96
MDL号 : MFCD00008028
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(567.68 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 100 mg/mL(540.65 mM)，配合低频超声助溶
生物活性
描述 2-Iodoacetamide, an alkylating agent, is widely employed for the alkylation of cysteine residues during the preparation of samples for proteomics analysis[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.41mL

1.08mL

0.54mL

27.03mL

5.41mL

2.70mL

54.07mL

10.81mL

5.41mL
参考文献

[1]Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16(9):3443-3447.

[2]J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr;109:905-8.