(S)-SNAP5114

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Chemical Structure| 157604-55-2 同义名 : -
CAS号 : 157604-55-2
货号 : A572954
分子式 : C30H35NO6
纯度 : 99%+
分子量 : 505.6
MDL号 : MFCD06411702
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(207.67 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 (S)-SNAP5114 is a selective GABA transporter inhibitor with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.98mL

0.40mL

0.20mL

9.89mL

1.98mL

0.99mL

19.78mL

3.96mL

1.98mL
参考文献

[1]Borden LA, et al. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site. Receptors Channels. 1994;2(3):207-13.

[2]Borden LA, et al. GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem Int. 1996 Oct;29(4):335-56.