Herniarin

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Chemical Structure| 531-59-9 同义名 : 7-Methoxycoumarin; Methyl umbelliferyl ether; NSC 404559; Methylumbelliferone; Gerniarin; Ayapanin; Herniarine
CAS号 : 531-59-9
货号 : A571905
分子式 : C10H8O3
纯度 : 97%
分子量 : 176.17
MDL号 : MFCD00006876
存储条件:

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(596.02 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 7-Methoxycoumarin, a natural product isolated and purified from the herbs of Citrus reticulata cv. Chachiensis, has potent antioxidant effect, strong hepatoprotective activity, and weak estrogenic activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

5.68mL

1.14mL

0.57mL

28.38mL

5.68mL

2.84mL

56.76mL

11.35mL

5.68mL

参考文献

[1]Zingue S, Michel T, et al. Estrogen-like and tissue-selective effects of 7-methoxycoumarin from Ficus umbellata (Moraceae): an in vitro and in vivo study. BMC Complement Altern Med. 2017 Aug 2;17(1):383.

[2]Sancheti S, Sancheti S, Seo SY. Ameliorative effects of 7-methylcoumarin and 7-methoxycoumarin against CCl4-induced hepatotoxicity in rats. Drug Chem Toxicol. 2013 Jan;36(1):42-7.