Oroxyloside

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Chemical Structure| 36948-76-2 同义名 : Oroxylin A-7-O-β-D-glucuronide; Oroxylin A-7-O-glucuronide
CAS号 : 36948-76-2
货号 : A570954
分子式 : C22H20O11
纯度 : 99%+
分子量 : 460.39
MDL号 : MFCD23379930
存储条件：

Pure form Inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(108.6 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Oroxylin A 7-O-beta-D-glucuronide, a natural product isolated and purified from the roots of Scutellaria regeliana Nakai., can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL, and inhibit 34% of total prolyl oligopeptidase (POP) activity, respectively at a concentration of 100 mM.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.17mL

0.43mL

0.22mL

10.86mL

2.17mL

1.09mL

21.72mL

4.34mL

2.17mL
参考文献

[1]Cai Y, Li S, et al. Oral pharmacokinetics of baicalin, wogonoside, oroxylin A 7-O-β-d-glucuronide and their aglycones from an aqueous extract of Scutellariae Radix in the rat. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 15;1026:124-33.

[2]Zhou XQ, Liang H, et al. [Flavonoids from Scutellaria baicalensis and their bioactivities] . Beijing Da Xue Xue Bao. 2009 Oct 18;41(5):578-84. Chinese.