p-Ethynylphenylalanine
产品说明书
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同义名 : | 4-Ethynyl-L-phenylalanine |
| CAS号 : | 278605-15-5 | |
| 货号 : | A564408 | |
| 分子式 : | C11H11NO2 | |
| 纯度 : | 97% | |
| 分子量 : | 189.21 | |
| MDL号 : | MFCD18252809 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 2 mg/mL(10.57 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 1M HCl: 250 mg/mL(1321.28 mM)，配合低频超声，并调节pH至1 1M NaOH: 200 mg/mL(1057.02 mM)，配合低频超声，并调节pH至11 |
| 生物活性 | |||
|---|---|---|---|
| 描述 | p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH), displaying a Ki value of 32.6 μM. This inhibition directly impacts the biosynthesis pathway of serotonin, effectively reducing its production[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
5.29mL 1.06mL 0.53mL |
26.43mL 5.29mL 2.64mL |
52.85mL 10.57mL 5.29mL |
| 参考文献 |
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