10074-A4

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Chemical Structure| 312631-87-1 同义名 : -
CAS号 : 312631-87-1
货号 : A561489
分子式 : C18H14Cl2N2O3S
纯度 : 95%
分子量 : 409.29
MDL号 : -
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 120 mg/mL(293.19 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 10074-A4 functions as a c-Myc inhibitor, binding to various sites along the peptide chain of c-Myc370-409. It possesses anticancer properties [1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.22mL

2.44mL

1.22mL

24.43mL

4.89mL

2.44mL
参考文献

[1]Chen Yu, et al. Structure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc. Sci Rep. 2016 Mar 2;6:22298.

[2]Fan Jin, et al. Ligand clouds around protein clouds: a scenario of ligand binding with intrinsically disordered proteins. PLoS Comput Biol. 2013;9(10):e1003249.