Adoprazine

产品说明书

Print
Chemical Structure| 222551-17-9 同义名 : SLV313
CAS号 : 222551-17-9
货号 : A548390
分子式 : C24H24FN3O2
纯度 : 98+%
分子量 : 405.46
MDL号 : MFCD11973649
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(123.32 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.47mL

0.49mL

0.25mL

12.33mL

2.47mL

1.23mL

24.66mL

4.93mL

2.47mL
参考文献

[1]Auclair AL, Kleven MS, et al. Differences among conventional, atypical and novel putative D(2)/5-HT(1A) antipsychotics on catalepsy-associated behaviour in cynomolgus monkeys. Behav Brain Res. 2009 Nov 5;203(2):288-95.

[2]Lange JH, Reinders JH, et al. Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem. 2007 Oct 18;50(21):5103-8.