Sotetsuflavone

产品说明书

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Chemical Structure| 2608-21-1 同义名 : -
CAS号 : 2608-21-1
货号 : A540392
分子式 : C31H20O10
纯度 : 98+%
分子量 : 552.49
MDL号 : -
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Sotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase) with an IC50 of 0.16 μM, is the most active compound of this series .
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.81mL

0.36mL

0.18mL

9.05mL

1.81mL

0.90mL

18.10mL

3.62mL

1.81mL
参考文献

[1]Coulerie P, Nour M, et al. Structure-activity relationship study of biflavonoids on the Dengue virus polymerase DENV-NS5 RdRp. Planta Med. 2013 Sep;79(14):1313-8.

[2]Li SH, Zhang HJ, et al. Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis. J Nat Prod. 2003 Jul;66(7):1002-5.