Indotecan
产品说明书
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同义名 : | LMP-400; NSC-724998 |
| CAS号 : | 915303-09-2 | |
| 货号 : | A521989 | |
| 分子式 : | C26H26N2O7 | |
| 纯度 : | 98% | |
| 分子量 : | 478.49 | |
| MDL号 : | MFCD25977124 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Indotecan is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01794104 | Neoplasm Lymp... 展开 >>homa 收起 << | Phase 1 | Completed | - | United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 << |
| NCT01051635 | Neoplasms Lym... 展开 >>phoma 收起 << | Phase 1 | Completed | - | United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.09mL 0.42mL 0.21mL |
10.45mL 2.09mL 1.04mL |
20.90mL 4.18mL 2.09mL |
