Ceftazidime

产品说明书

Print
Chemical Structure| 72558-82-8 同义名 : GR20263
CAS号 : 72558-82-8
货号 : A516848
分子式 : C22H22N6O7S2
纯度 : 98%
分子量 : 546.58
MDL号 : MFCD00072034
存储条件：

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 100 mg/mL(182.96 mM)，配合低频超声助溶
生物活性
描述 Ceftazidime (GR20263) is an antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative aerobic bacteria. It shows effectiveness against Enterobacteriaceae, including β-lactamase-positive strains, and is resistant to hydrolysis by most β-lactamases[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.83mL

0.37mL

0.18mL

9.15mL

1.83mL

0.91mL

18.30mL

3.66mL

1.83mL
参考文献

[1]Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61.

[2]Esmat Kamali, et al. In vitro activities of cellulase and ceftazidime, alone and in combination against Pseudomonas aeruginosa biofilms. BMC Microbiol. 2021 Dec 16;21(1):347.

[3]Qiuxia Lin, et al. Avibactam potentiated the activity of both ceftazidime and aztreonam against S. maltophilia clinical isolates in vitro. BMC Microbiol. 2021 Feb 22;21(1):60.

[4]Shawn H MacVane, et al. Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-β-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother. 2014 Nov;58(11):7007-9.