N-Succinimidyl-S-acetylthioacetate

产品说明书

Print
Chemical Structure| 76931-93-6 同义名 : SATA
CAS号 : 76931-93-6
货号 : A508892
分子式 : C8H9NO5S
纯度 : 98%+
分子量 : 231.23
MDL号 : MFCD00036891
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(454.1 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 N-Succinimidyl S-acetylthioacetate (SATA), a protein modification reagent, introduces thiol groups into protein molecules. SATA adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form[1][2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.32mL

0.86mL

0.43mL

21.62mL

4.32mL

2.16mL

43.25mL

8.65mL

4.32mL
参考文献

[1]J.L.MHeeremans, et al. Interference of ϵ-amino-caproic acid with [N-succinimidyl S-acetylthioacetate derived] thiol-introduction into glu-plasminogen. Volume 8, Supplement 2, 1994, Pages 138-141.

[2]Allen KJH, et al. Evaluation of N-Succinimidyl S-Acetylthioacetate Ligand for Radiolabeling of HumanizedAntibodies with 188Rhenium. Cancer Biother Radiopharm. 2018 Oct;33(8):349-355.