Naringin dihydrochalcone

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Chemical Structure| 18916-17-1 同义名 : 柚皮甙二氢查尔酮 ;Naringin DC
CAS号 : 18916-17-1
货号 : A504448
分子式 : C27H34O14
纯度 : 97%
分子量 : 582.55
MDL号 : MFCD08436145
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(180.24 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Naringin Dihydrochalcone, an artificial sweetener derived from naringin—a prominent flavanone glycoside found in tomatoes and various citrus fruits—displays a range of biological activities including antioxidant, anti-inflammatory, and antiapoptotic effects. It notably impedes the NF-κB signaling pathway[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.72mL

0.34mL

0.17mL

8.58mL

1.72mL

0.86mL

17.17mL

3.43mL

1.72mL
参考文献

[1]Chen F, et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. PLoS One. 2015 Nov 30;10(11):e0143868.

[2]Raha S, et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. Int J Oncol. 2015 Sep;47(3):1061-9.

[3]Kulasekaran G, et al. Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. Mol Cell Biochem. 2015 Nov;409(1-2):199-211.