Carbetocin

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Chemical Structure| 37025-55-1 同义名 : Carbetocin游离态 ;Carbetocin Acetate
CAS号 : 37025-55-1
货号 : A504288
分子式 : C45H69N11O12S
纯度 : 98+%
分子量 : 988.16
MDL号 : MFCD01076600
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 30 mg/mL(30.36 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 30 mg/mL(30.36 mM)
生物活性
描述 Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth and an agonist at peripheral oxytocin receptors.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.01mL

0.20mL

0.10mL

5.06mL

1.01mL

0.51mL

10.12mL

2.02mL

1.01mL
参考文献

[1]Khan M, Balki M, et al. Carbetocin at elective Cesarean delivery: a sequential allocation trial to determine the minimum effective dose. Can J Anaesth. 2014 Mar;61(3):242-8.

[2]Su LL, Chong YS, et al. Carbetocin for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2012 Feb 15;(2):CD005457.