Bisandrographolide A

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Chemical Structure| 160498-00-0 同义名 : BAA
CAS号 : 160498-00-0
货号 : A490830
分子式 : C40H56O8
纯度 : 99+%
分子量 : 664.87
MDL号 : MFCD22417323
存储条件：

Pure form

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Bisandrographolide A, a natural product, activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.50mL

0.30mL

0.15mL

7.52mL

1.50mL

0.75mL

15.04mL

3.01mL

1.50mL
参考文献

[1]Vriens J, Owsianik G, et al. Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. J Biol Chem. 2007 Apr 27;282(17):12796-803.

[2]Smith PL, Maloney KN, et al. Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem. 2006 Oct 6;281(40):29897-904.