(+)-Nootkatone

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Chemical Structure| 4674-50-4 同义名 : (+)-诺卡酮 ;Nootkatone
CAS号 : 4674-50-4
货号 : A490178
分子式 : C15H22O
纯度 : 98%
分子量 : 218.33
MDL号 : MFCD04974578
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(480.91 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
动物实验配方：
生物活性
描述 Nootkatone, a natural product isolated and purified from the rhizoma of Bupleurum longibrachiatum Turcz., can prevent obesity and improve physical performance through AMPK activation in skeletal muscle and liver.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.58mL

0.92mL

0.46mL

22.90mL

4.58mL

2.29mL

45.80mL

9.16mL

4.58mL
参考文献

[1]Choi HJ, Lee JH, Jung YS. (+)-Nootkatone inhibits tumor necrosis factor α/interferon γ-induced production of chemokines in HaCaT cells. Biochem Biophys Res Commun. 2014 May 2;447(2):278-84.

[2]Bharadwaj A, Stafford KC 3rd, Behle RW. Efficacy and environmental persistence of nootkatone for the control of the blacklegged tick (Acari: Ixodidae) in residential landscapes. J Med Entomol. 2012 Sep;49(5):1035-44.