Liriodenine

产品说明书

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Chemical Structure| 475-75-2 同义名 : Spermatheridine; VLT045
CAS号 : 475-75-2
货号 : A470859
分子式 : C17H9NO3
纯度 : 97%
分子量 : 275.26
MDL号 : MFCD00936501
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Liriodenine, a natural product isolated and purified from the barks of Liriodendron chinense (Hemsl.) Sarg., with anti-fungal activity, inhibits progression of the CAOV-3 cell cycle in S phase and exhibits potent antitumor activities in laryngocarcinoma HEp-2 cells, in vitro and in vivo, via the upregulation of p53 expression.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.63mL

0.73mL

0.36mL

18.16mL

3.63mL

1.82mL

36.33mL

7.27mL

3.63mL
参考文献

[1]Li L, Xu Y, Wang B. Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression. Oncol Lett. 2015 Mar;9(3):1121-1127.

[2]Nordin N, Majid NA, et al. Liriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progression. Drug Des Devel Ther. 2015 Mar 10;9:1437-48.