Dropropizine

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Chemical Structure| 17692-31-8 同义名 : UCB-196; (±)-Dropropizine
CAS号 : 17692-31-8
货号 : A464373
分子式 : C13H20N2O2
纯度 : 98% NMR
分子量 : 236.31
MDL号 : MFCD00079124
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 40 mg/mL(169.27 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 30 mg/mL(126.95 mM)
生物活性
描述 Dropropizine is a racemic non-opiate antitussive agent which has been used clinically for many years.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.23mL

0.85mL

0.42mL

21.16mL

4.23mL

2.12mL

42.32mL

8.46mL

4.23mL
参考文献

[1]Sutovska M, Franova S, et al. The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways. Bratisl Lek Listy. 2009;110(5):269-75.

[2]Slamenova D, Budayova E, et al. Results of genotoxicity testing of mazindol (degonan), lithium carbonicum (contemnol) and dropropizine (ditustat) in Chinese hamster V79 and human EUE cells. Mutat Res. 1986 Mar;169(3):171-7.